What Are The Chances Of Surviving Cancer

What Are The Chances Of Surviving Cancer – Every year, 17 million people around the world hear these terrifying words. Moments with doctors change their lives and deeply affect those close to them. Stories about people with cancer, as well as highlights of ongoing research into the disease, are always in the news. Whether it’s exciting new drugs, precise robotic surgery, or therapy using genetically engineered cells, cancer sufferers have reason to hope for the future.

Survival chances for most cancers are steadily increasing worldwide, with some serious exceptions such as pancreatic cancer, where your chances of long-term survival are very low, regardless of where you live . In the UK, fifty percent of people can expect to live ten years or more after a cancer diagnosis. However, for any cancer treatment to be successful, an individual must interact with a complex network of medical services and make hundreds of decisions with healthcare professionals that lead to diagnosis, diagnosis, treatment, indications and ultimately life after cancer. But how well these systems work for individuals varies widely, not just around the world, but sometimes among people living on the same street, who expect the same standards.

What Are The Chances Of Surviving Cancer

To explore why these differences exist and to investigate the important questions of the long-term impact of cancer on survivors of the disease, a diverse group of researchers are working on cancer survival at the School of Tropical & Tropical Medicine. They often work with huge data sets, from 37 million cancer patients worldwide, investigating everything from survival patterns, the mental health effects of surviving cancer, or the effects of cancer, the long-term physical effects of cancer drugs and the course possible cancer. for the individual. patient.

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“We are not the kind of cancer scientists people think. We don’t wear lab coats and look down under the microscope. What we study is, once people get cancer, how long they live. Camille Marinege, researcher and statistician in the Cancer Survivors Group at .

The main goal of the Cancer Survival Team is to understand why these differences in cancer survival rates occur and to devise strategies to combat them. The international group has more than 30 researchers and is the largest group of its kind in the world. Professor Michel Coleman is a leader and has worked in the field of cancer epidemiology research for over three decades.

“For each type of cancer, we looked for patterns and inequalities in survival rates depending on where you live, rich or poor neighborhoods, young or old,” said Professor Coleman and especially the difference in survival rates with other countries.” .

“We’re not the kind of cancer scientists that people think of. We don’t wear lab coats or look down a microscope. What we’re studying is, when someone has cancer, we don’t need to write, how long they lived.” Camille Marine, Research Fellow at

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For example, the researchers found that five-year survival rates for breast, colorectal and lung cancer were lower in the UK than in countries with similar taxpayer-funded healthcare, such as the Nordic countries, Canada and the Australia. The difference was found to be partly due to later diagnosis, which is known to lead to worse outcomes. However, this does not explain all the differences in survival rates.

Professor Coleman said: “We have shown that patients tend to be diagnosed at a later stage in the UK, but even at a specific stage of diagnosis, survival rates in this country are also low.

This is particularly surprising, indicating that treatments for patients with the same disease are worse in the UK than in the Nordic countries. These insights eventually led to the development of the National Early Detection and Awareness Initiative (NAEDI) in 2008, which sought to improve cancer diagnosis, highlighting the potential power of big data to make real changes. creation in society if useful use is made of the information.

Professor Coleman said: “Our research into cancer survival underpins national cancer strategies which specifically aim to improve survival based on our findings”.

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Although the team rarely receives information about the specific drugs used, as this detail is not usually stored in cancer registries, they can sometimes see the effects of new targeted cancer treatments as they are rolled out. The track record of these drugs in the data set shows the highest survival rates for certain types of cancer.

“When a relatively simple, rapidly available treatment is significantly more effective than previous approaches, you see a spike in survival rates in certain populations,” Professor Coleman said.

Imatinib is the first cancer drug developed to specifically target a protein that is present on myeloid leukemia cells, but rare or absent on other cell types. Introduced in 2001, first in the United States and soon worldwide, it greatly increased the long-term survival of patients with chronic myeloid leukemia.

However, the scope and impact of the Cancer Survival Group’s research goes far beyond just a few countries. An ambitious research program aimed at global monitoring of population-based cancer survival trends, called CONCORD, collects and analyzes cancer data from countries around the world to identify trends and differences in survival rates.

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In 2008, which involved data from 1.9 million people with four different types of cancer in 31 countries. The most recent study, CONCORD-3, involved data from 37.5 million cancer patients diagnosed with one of 18 different cancers between 2000-2014, representing three quarters of the total number of cancer diagnoses worldwide each year and covers a living population only. billion. in 71 countries.

Dr Claudia Allemani, who led the CONCORD program with Professor Coleman, said: “We are processing the world’s largest population-based database of individual records from cancer patients. “We saw a steady upward trend in survival rates for breast and colorectal cancer between 1995 and 2014. Overall, survival rates are increasing worldwide for most types of cancer, but some cancers such as lung, liver , and a pancreas in which to live. not improved. sad story.”

In another case, the huge database showed that the 5-year survival rate in Southeast Asian countries was higher than in other countries for gastrointestinal cancer, such as stomach and esophagus cancer, but lower for skin cancer and blood cancer. Higher gastrointestinal cancer survival rates may be related to comprehensive screening and treatment programs in the region, but low survival rates for melanoma and leukemia are being investigated. Using such differences to allow health care systems to learn from each other was a key goal of the researchers. To do this, healthcare systems and governments must have robust information about their operations to develop effective strategies and policies.

“When you are looking at a country with a high survival rate, you would go to test the health system, see how it is doing and try to turn what the system is doing well to another country”.

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Spending is a common topic in healthcare systems around the world. In terms of cost, research shows that existing health care budgets are not directly proportional to cancer survival rates.

“Cancer survival rates in Canada and the United States are about the same, even if costs are much higher in the United States than in Canada. If you compare Canada and Sweden, spending in Sweden is even lower, but survival rates are very similar. That’s an important message – not just how much money is allocated to health, but also

The team also looked at differences in cancer survival rates between people across countries, based on factors such as ethnicity and socioeconomic information such as wealth and education. What they have achieved is amazing, even in some of the richest countries in the world.

With colleagues at the US Centers for Disease Control and Prevention, examining racial differences in survival between blacks and whites. Survival rates in blacks are consistently lower than in whites in the United States for almost all cancers. They note that blacks are often diagnosed at a later stage than whites, but that this alone does not necessarily explain the large difference in survival rates.

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“Even with breast cancer, which is considered to have a good prognosis, you see a big difference in survival between white women and black women. The high rate of triple-negative breast cancer, (an aggressive type that is often diagnosed at a later stage), in black women cannot be the only explanation for the large disparity in survival rates. Especially since we see this difference for most cancers,” said Dr. German.

Dr. Allemani also significant differences in cancer survival rates for women around the world. This piqued her interest and she is currently leading a global project focusing particularly on breast, cervical and ovarian cancer in women. CONCORD data would allow her to answer a number, but no

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